• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    There are disclosed N-aryl-1,3-oxazolidine-2,4-diones of the formula: <IMAGE> wherein: R=C1-C5 alkyl; C1-C5 haloalkyl Y=H; hydrogen, 3,4-dichloro; 3,5-dichloro; 3,5-difluoro; 3,5-dimethyl; 3,5-dimethoxy; 3,5-bis-trifluoromethyl; and A= <IMAGE> wherein R is as previously defined. The N-aryl-1,3-oxazolidine-2,4-diones are useful fungicides, possess systemic action, and are particularly active in the field.
    公开号:SU1077555A3
    申请号:SU802861957
    申请日:1980-01-03
    公开日:1984-02-29
    发明作者:Ди Торо Винценцо；Гоццо Франко；Чечере Миралл；Лоруссо Симоне；Гаравалья Карло
    申请人:Монтэдисон С.П.А. (Фирма)；
    IPC主号:
    专利说明:


    SP
    JV JV
    The invention relates to a method for controlling or preventing diseases of cultivated plants caused by fungi by means of N-phenyl-1, 3-oxazolidin-2,4-diones, substituted in the 5-position.
    There is a method of controlling fungal diseases of plants with. N- (3,5-dichlorophenyl) 5,5-dimethyl-1, 3-oxazolidin-2,4-dione Sclex preparation ij.
    However, this drug has harmful side effects on people.
    There is a known method for controlling the fungal diseases of tomato, grape and earth plants caused by Botrytis cinerea and Plasmopara viticola, including treating plants by spraying with a preparation based on the H-phenyl-1,3-oxazolidin-2, 4-dione derivative, N- (3,5-dichlorophenyl) -5-methyl-5-vinyl-1,3-oxazolidin-2, 4-dione - Vinchlozolin 2.
    However, the known method has insufficient fungicidal action.
    The purpose of the invention is to enhance the fungicidal action.
    This goal is achieved by using a compound of the general formula N-1, 3-oxazolidine-2,4-dione as an I-fe derivative;
    Usually use solutions in the amount of 1000 l / ha.
    Example 1. The biological activity of the proposed compounds.
    a) In vitro activity. Activity is determined by quantifying the percentage of growth of fungi cultured in soil containing increased amounts of the test compounds. These compounds are introduced 0 in the form of dispersions with dimethyl rulfoxide and Tween 20 so that the final concentration is 0.5% in dimethyl sulfoxide and 0.01% in Guinea 20. 5
    For samples of bacteria, such as Botrytis cinerea, Monilia fructigena, Penic.illium it licum and Aspergillus parassiticum, 1 drop of spore suspension 0 and the mycelium is placed in the center of the Petri dish containing the soil treated with fungus (pD Agar Difso), thus obtaining a circular inoculation. After 4 days of growth 5, the diameters of the developing colonies are measured and the percentage growth of the population relative to the untreated control samples is calculated.
    0 For Helminthosporium Maydis, Helminthosporium oryzae and Alternaria tenuis samples, 100 ml of spore suspension of the mycelium is added to test tubes, containing 10 cm of potato broth (Difco), which are kept in a horizontal position and incubated for 7 days at 25 s. After this time (after intensive mixing)
    0, the percent growth of a population of fungi is calculated by placing the tubes vertically one next to the other.
    In tab. 1 shows the fungicidal
    5 activity in vitro.
    Table 1
    M- (3,5-Dichlorophenyl) -5-methyl-5-carbomethoxy-1, 3-oxazo-lidin-2, 4 All weighs 10 H- (3,5-Di-. Chlorophenyl) -5-methyl-5- 1-carbethoxy-1, 3-oxazshshidin-2, 4sse 10 -dione H- (3,5-dichlorophenyl) -5-ethyl-5-carbethoxy-2 -1-oxaeolidin-2, 4sse sceLciHVuOCjts ;. 10 N-C3,5-Dichlorophenyl) -5-methyl-5-carbo-n, propoxy-1, 3-oxazolidin-2,4-DI-
    b) Preventive activity against Botrytis cinerea and tomato sprouts.
    Both sides of the leaf of tomato sprouts (cv. Marmande), cultivated in pots in a conditioned medium at 60% relative humidity, were polluted with a water-acetone solution (20% by volume of acetone) of the compounds under study. A day later, infection is carried out by grafting a suspension of Botrytis cinerea in carrot broth (1,000,000 spores / cm) in
    Both leaf surfaces. After aging for 24 hours in a humidified medium at 26 ° C, the plants are transferred to an environment having 70% relative humidity for an incubation period (6 days). The extent of infection is assessed visually using scores on a scale from 100 (healthy plant) to O (fully contaminated plant).
    The results are shown in Table. 2. 0 0 0
    AP "5Сг СН, OCjH
    B) Preventive activity against Plasmopara vtiticola on growth — like grapes.
    Leaves of grapes (cv. Doicetto) grown in pots; in a conditioned medium at 25 ° C and 60% relative humidity, polluted on both sides with water-, acetone (20% vol. acetone) solutions of the same test substances. Twenty-four hours after treatment, the lower side of the leaves was sprayed with aq. N- (3-Chlorophenyl) -5-methyl-5-carbethoxy-1, 3-oxace with% zolidin-2,4-dione H- (3,5-Methoxyphenyl ) -5-methyl-5-carbethoxy-1, 3g 3-OCH 5 OCZZ, CH-oxazolidin-1,4-dione N- (3,5-Dichlorophenyl) -5-ethyl-5-carbethoxy-1, W- Oxazolidin-2,4. All-CjjH N- (3,5-Dichlorophenyl) -5-methyl-5-carboxy-n. Propoxy-1, Z-oxazolidin-2,4zev see N- (3,5-Dichlorophenyl) -5-methyl-5-carboisopropoxy-1, -3-oxazolindin 5Se 0% -2,4-dione N- (3,5-Dimethoxyphenyl.) - 5-carbethoxy-1, 3-oxa3-OCH 5-OCH H, zolidin-2, 4-dion Vinchlozolin
    table 2
    100
    100
    100
    95
    suspension of conidium Plasmopara 5 viticola (200,000 conidia / cm). After 24 hours of soaking in a humid-saturated medium, the shoots are transferred to the medium from 70% relative humidity during an incubation period (7 days). The intensity of infection is assessed according to indices of an assessment scale of 100 units. (healthy plant) to O (fully inhaHeijHoe. plant).
    The results are shown in Table. 3
    Table 3 Sn OC.gHg CgHj OS5 "5 OS% OCjHg 100
    Example 2. Systemic protective activity on strawberry and tomato plants.
    Strawberry plants (variety Saunk: thaw) and tomatoes (variety Marmande) grown in pots under ambient conditions at a relative humidity of 60% are tested by adding to the soil a water dispersion of the products offered, each of which is prepared in the form of a wettable powder with active base concentration of 20%.
    Plants are conditioned and seven days after treatment, both sides
    N- (3,5-Dichlorophenyl) -5-methyl-5-carboethoxy-1, 3-oxazolidin-2, 4-dione
    H- (3,5-Difluorophenyl) -5-methyl-5-carboethoxy-i, 3-oxazolidin-2, 4-dione
    N- (3,5-Dichlorfeni: 5-ethyl-5-carbomethoxy-1, 3-oxazolidin-, 4-dione
    H- (3,5-Dichlorophenyl) -5,5-dime-1, 3-oxazolidin-2,4-dione
    Vinchlozolin
    The proposed compounds are more active than the known, in relation to
    leaves are infected by spraying Botrytis cinerea conidia suspensions in carrot broth (1,000,000 conidia / ml) ..
    After 14 days of incubation on strawberry plants and 8 days on tomatoes, plant infection is evaluated on a scale from 0 (completely infected plants) to 100 (no follow up).
    in tab. 4 shows the results of tests for systemic activity when absorbed through the roots on tomato and strawberry plants infected with Botrytis cinerea, after 8 and 14
    days after processing.
    Table.4
    100
    100 100
    . 100 100
    100
    oh oh
    oh oh
    of infectious diseases, which are reported by Botrytis and Plasmopara.
    权利要求:
    Claims (1)
    [1]
    METHOD FOR FIGHTING FUNGAL DISEASES OF TOMATO, VINE AND STRAWBERRY PLANTS CAUSED BY BOTRYTIS CINEREA AND PLASMOPARA VITI- U COLA, including treatment of plants by spraying with a drug based on the derivative of N-phenyl- 1 -phenyl-3-yl, !, . characterized in that, in order to enhance the fungicidal action, a compound of the general formula is used as a derivative of m-phenyl-1,3-oxazolidine-2,4-dione
    A
    01 ....... 4 'Cf R where I' - Cg, OCH $ ', ’
    R 2 - Cg, OCH
    R is oens, os, n 5 , os-n 7 ;
    A - CH 3 , C 4 H 5 / in a concentration of 0.037-0.3 wt.% In the preparation.
    SU ,,,, 1077555
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